G-418 Disulfate (20 ml bottle)

CAS#: 108321-42-2

• Used as a selection antibiotic in cell culture gene selection applications
• Prevents protein synthesis by blocking the elongation step in prokaryotic and eukaryotic ribosomes
• Concentration:  50mg/ml
• This product cannot be shipped to a private residence.

G418 DiSulfate Solution is routinely used as a selection antibiotic in cell culture gene selection applications. G418 solution is an aminoglycoside antibiotic isolated fromMicromonospora rhodorangeaand is closely related to the gentamicins; most notably, genatmicin B1. G418 is a generic name of Geneticin®.

_____________________________________________________________________________________________________

Molecular Formula:    C₂₀H₄₀N₄O₁₀ · 2H₂SO₄
Molecular Weight:   692.71 g/mol
Appearance:   Clear, colorless solution
Source:  Biosynthetic: produced byMicromonospora rhodorangea
pH (@25°C):  4.6 - 6.0
Optical Rotation:  +104° - +121°
Storage:  2-8°C
Concentration:  50 mg/ml

C₂₀H₄₀N₄O₁₀ · 2H₂SO₄
_____________________________________________________________________________________

Aminoglycoside antibiotic.
Toxic to both prokaryotic and eukaryotic cells.

Application
Use as selective agent in Transformation.
Used for selecting eukaryotic expression vectors with related resistance genes.